Jun 22, 2023
One common cause of vitamin B12 deficiency in men is a lack of dietary intake of foods rich in vitamin B12, such as meat, fish, eggs, and dairy products.
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Certain gastrointestinal disorders, such as Crohn's disease, celiac disease, and gastric bypass surgery, can affect the absorption of vitamin B12 in the body, leading to deficiency.
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Pernicious anaemia, an autoimmune condition, can interfere with the production of intrinsic factor, a protein necessary for the absorption of vitamin B12 in the intestines.
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As men age, the production of stomach acid and intrinsic factors can decline, impairing the absorption of vitamin B12 from food sources and increasing the risk of deficiency.
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Chronic alcohol consumption can damage the lining of the stomach and impair the production of intrinsic factors, resulting in decreased absorption of vitamin B12.
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Certain medications, such as proton pump inhibitors (PPIs) and metformin (used to treat diabetes), can interfere with vitamin B12 absorption or increase its excretion, leading to deficiency.
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Men with malabsorption syndromes, such as inflammatory bowel disease or pancreatic insufficiency, may have impaired absorption of vitamin B12.
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Infections caused by parasites, such as fish tapeworm or giardia lamblia, can interfere with the absorption of vitamin B12 and contribute to deficiency in men.
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Some rare genetic disorders, like transcobalamin deficiency or homocystinuria, can affect the metabolism or transport of vitamin B12, leading to deficiency in affected men.
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Men who follow strict vegetarian or vegan diets are at a higher risk of developing vitamin B12 deficiency, as plant-based foods do not provide sufficient amounts of this vitamin.
Credit: Stay Young Bureau
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