Dermatomyositis: What It Is, Causes, Symptoms, And Treatment

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Dermatomyositis: What It Is, Causes, Symptoms, And Treatment

Dermatomyositis: What it is, causes, symptoms, and treatment

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Dermatomyositis is an autoimmune and a chronic inflammatory disorder that primarily affects the muscles and skin. It falls under the category of idiopathic inflammatory myopathies (IIMs), a group of autoimmune diseases characterised by muscle inflammation. It is a rare disease, affecting about 2 to 10 people per million each year. Dermatomyositis can occur at any age, but it is most common in adults between the ages of 40 and 60. Although the exact cause of dermatomyositis remains unknown, researchers believe it to be a combination of genetic and environmental factors.

Symptoms of Dermatomyositis

The symptoms of dermatomyositis can vary from person to person, but they typically appear as muscle weakness and skin changes. Muscle weakness is often progressive and can affect various muscle groups, including those in the limbs, neck, and trunk. The weakness may make it challenging to perform everyday activities such as climbing stairs or lifting objects.

Skin changes are other symptoms of dermatomyositis. A distinct rash, known as a heliotrope rash, may appear on the eyelids, giving them a purplish hue. Gottron's papules, which are raised, scaly patches, can also develop on the knuckles, elbows, and knees. Other skin manifestations include a reddish or bluish discoloration on the hands and fingers, swelling, and calcinosis, which is the formation of calcium deposits under the skin.

Here are additional symptoms that you may encounter:

  • Muscular discomfort
  • Sensitivity or soreness in the muscles
  • Difficulties with swallowing
  • Respiratory issues affecting the lungs
  • Formation of firm calcium deposits beneath the skin, commonly observed in children
  • Persistent fatigue
  • Inadvertent weight loss
  • Presence of fever

Causes of Dermatomyositis

While the precise cause of dermatomyositis remains unknown, researchers have identified several factors that may contribute to its development. Genetics is thought to play a role, as certain genetic variations have been associated with an increased risk of developing the condition. Environmental triggers, such as infections or exposure to certain medications, may also activate the immune system and lead to the onset of dermatomyositis. Dermatomyositis is thought to be an autoimmune disorder meaning that the body's immune system mistakenly attacks healthy cells. In the case of dermatomyositis, the immune system attacks the muscles and skin.


Diagnosing dermatomyositis can be challenging due to its rarity and overlapping symptoms with other conditions. A thorough physical examination, combined with blood tests to measure muscle enzymes and autoantibodies, is often the first step in the diagnostic process. Your physician might request the following tests:

  • Magnetic Resonance Imaging (MRI) to detect any irregularities in the muscles
  • Electromyography (EMG) to record the electrical signals responsible for muscle control
  • Blood analysis to assess muscle enzyme levels and autoantibodies, which are antibodies that target healthy cells
  • Muscle biopsy to examine muscle tissue samples for signs of inflammation and other disease-related issues
  • Skin biopsy to examine skin samples for disease-induced changes

Treatment options 

Treatment for dermatomyositis aims to alleviate symptoms, prevent disease progression, and manage complications. A multidisciplinary approach involving rheumatologists, dermatologists, and physical therapists is often necessary. Medications such as corticosteroids and immunosuppressants are commonly prescribed to reduce inflammation and suppress the immune system's overactivity. Physical therapy and exercise can help improve muscle strength and mobility. In severe cases, intravenous immunoglobulin (IVIG) or biologic therapies may be recommended. Certain lifestyle changes can also help to manage dermatomyositis which include eating a healthy diet, regular exercise, avoiding smoking and alcohol. With early diagnosis and treatment, most people with dermatomyositis can live normal, active lives.

Associate complications

Dermatomyositis is associated with various complications arising from muscle weakness and skin issues. Here are several commonly encountered problems:

  • Development of skin ulcers
  • Formation of gastric ulcers
  • Difficulty in breathing
  • Susceptibility to lung infections
  • Challenges with swallowing
  • Risk of malnutrition
  • Weight loss


Dermatomyositis is a complex autoimmune disease that affects the muscles and skin. While its exact causes remain unknown, advancements in research have led to improved diagnostic methods and treatment options. With ongoing research and support, the future holds promise for improved therapies and a better quality of life for those affected by this challenging condition.

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